Tools and Resources Which Anticoagulant? Image Library Atherothrombosis Coagulation Cascade Haemostasis Pulmonary Embolism Venous Thrombosis Audio Library Venous Thromboembolism Audio Library Prevention of stroke in patients with atrial fibrillation and comorbidities Audio Library Video Library See Also Peripheral Artery Disease: causes and consequences Coronary Artery Disease: causes and consequences Peripheral Artery Disease: causes and consequences Peripheral Artery Disease: causes and consequences Coronary Artery Disease: causes and consequences Coronary Artery Disease: causes and consequences Breadcrumb Image Library Coagulation Cascade Image Library Coagulation Cascade Anticoagulants - coagulation cascadeVitamin K antagonists lower levels of factors II, VII, IX and X. The heparins and fondaparinux work... Download PDFPPTXDOCXXLSXMP4ZIPJPGPNG Cascade overviewAn overview of the coagulation cascade, showing the initiation, propagation, and clot formation phases Download PDFPPTXDOCXXLSXMP4ZIPJPGPNG Clotting formation - coagulation cascadeThrombin converts fibrinogen to fibrin monomers which polymerize to form fibrin strands, Factor XIII... Download PDFPPTXDOCXXLSXMP4ZIPJPGPNG Fibrinolysis Plasminogen activators from injured endothelium convert plasminogen to plasmin which in turn breaks up the... Download PDFPPTXDOCXXLSXMP4ZIPJPGPNG Initiation - coagulation cascade Clotting is initiated by the activation of Factor VII by membrane-bound tissue factor. This leads to... Download PDFPPTXDOCXXLSXMP4ZIPJPGPNG Natural inhibitors The natural inhibitors of coagulation include tissue factor pathway inhibitor (TFPI), activated protein C... Download PDFPPTXDOCXXLSXMP4ZIPJPGPNG Propagation - coagulation cascade Activated Factor X, functioning as part of the prothrombinase complex on the surface of activated... Download PDFPPTXDOCXXLSXMP4ZIPJPGPNG