Real-World Evidence

Expanding real-world knowledge

Clinical trials have defined study protocols and strict patient inclusion and exclusion criteria. As a result, outcomes of clinical trials may not always fully reflect outcomes in routine clinical practice. Registries and non-interventional studies serve many important functions including:

• Identifying unmet patient needs
• Verifying the safety and efficiency of newly introduced therapies
• Providing information on the management of adverse events, e.g. bleeding, in routine clinical practice
• Understanding of treatment patterns

Several major medical registries and non-interventional studies have been launched in therapy areas in which anticoagulant therapy is used, including:

• Stroke prevention in patients with AF
• Secondary prevention of ACS
• Prevention and treatment of VTE